Tag: biology cells quiz
Adaptation of an ELISA assay for detection of IgG 2a responses against therapeutic monoclonal antibodies in a mouse immunization model
Biotherapeutic monoclonal antibodies (mAb) play important roles in clinical medicine but their potential to elicit immune responses in patients remains a major issue. In a study designed to investigate the effect of aggregation on immunogenic responses, mice were immunized with two monoclonal antibodies (mAb1 and mAb2). Serum levels of total IgG, IgG1, and IgG2a were measured …
Commercially Obtainable ELISA Kits for Measuring Adalimumab and Anti-adalimumab

A Comparative Analysis of 4 Commercially Obtainable ELISA Kits for Measuring Adalimumab and Anti-adalimumab Antibodies Background: Therapeutic drug monitoring of tumor necrosis issue inhibitors, resembling adalimumab, is more and more being carried out for the administration of autoimmune ailments. Nevertheless, there might be vital variation in drug and antibody concentrations obtained by totally different assay strategies. The intention …
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